Insight on Infections in Diabetic Setting

Author:

Pari Bianca1,Gallucci Matteo1,Ghigo Alberto1,Brizzi Maria Felice1ORCID

Affiliation:

1. Department of Medical Sciences, University of Turin, Corso Dogliotti 14, 10126 Turin, Italy

Abstract

The correlation between diabetes mellitus and infectious diseases is widely recognized. DM patients are characterized by the impaired function of the immune system. This translates into the occurrence of a variety of infections, including urinary tract, skin and surgical site infections, pneumonia, tuberculosis, and, more recently, SARS-CoV-2. Hyperglycemia has been identified as a relevant factor contributing to unfavorable outcomes in hospitalized patients including SARS-CoV-2 patients. Several studies have been performed proving that to maintain the proper and stringent monitoring of glycemia, a balanced diet and physical activity is mandatory to reduce the risk of infections and their associated complications. This review is focused on the mechanisms accounting for the increased susceptibility of DM patients to infections, with particular attention to the impact of newly introduced hypoglycemic drugs in sepsis management.

Publisher

MDPI AG

Subject

General Biochemistry, Genetics and Molecular Biology,Medicine (miscellaneous)

Reference145 articles.

1. Definition, Classification and Diagnosis of Diabetes Mellitus;Petersmann;Exp. Clin. Endocrinol. Diabetes,2019

2. Aschner, P., Basit, A., Fawwad, A., Guariguata, L., James, S., Karuranga, S., Malanda, B., Mbanya, J.C., O’neill, S., and Ogle, G. (2023, January 28). IDF Guide for Diabetes Epidemiology Studies IDF Guide for Diabetes Epidemiology Studies i Acknowledgements Authors. Available online: https://diabetesatlas.org/idf-guide-for-epidemiology-studies/.

3. (2023, January 28). IDF Diabetes Atlas 10th Edition. Available online: www.diabetesatlas.org.

4. Diabetes and Sepsis: Preclinical Findings and Clinical Relevance;Schuetz;Diabetes Care.,2011

5. Diabetes, Infection Risk and COVID-19;Erener;Mol. Metab.,2020

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