Bacterial Pathogens Causing Pneumonia Post Hematopoietic Stem Cell Transplant: The Chronic GVHD Population

Author:

Chaaban Said12,Zimmer Andrea3,Bhatt Vijaya Raj4,Schmidt Cynthia5,Sadikot Ruxana T.12

Affiliation:

1. VA Nebraska Western Iowa Health Care System, Omaha, NE 68105, USA

2. Division of Pulmonary, Critical Care & Sleep, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA

3. Division of Infectious Diseases, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA

4. Division of Hematology and Oncology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA

5. McGoogan Health Sciences Library, University of Nebraska Medical Center, Omaha, NE 68198, USA

Abstract

Allogeneic stem cell transplantation is a lifesaving treatment for many malignancies. Post-transplant patients may suffer from graft versus host disease in the acute and/or the chronic form(s). Post-transplantation immune deficiency due to a variety of factors is a major cause of morbidity and mortality. Furthermore, immunosuppression can lead to alterations in host factors that predisposes these patients to infections. Although patients who receive stem cell transplant are at an increased risk of opportunistic pathogens, which include fungi and viruses, bacterial infections remain the most common cause of morbidity. Here, we review bacterial pathogens that lead to pneumonias specifically in the chronic GVHD population.

Funder

Merit Review Award

RO1 funding

Publisher

MDPI AG

Subject

Infectious Diseases,Microbiology (medical),General Immunology and Microbiology,Molecular Biology,Immunology and Allergy

Reference56 articles.

1. Major pulmonary complications after hematopoietic stem cell transplant;Diab;Exp. Clin. Transplant.,2016

2. Worldwide Network for Blood & Marrow Transplantation (WBMT) special article, challenges facing emerging alternate donor registries;Aljurf;Bone Marrow Transplant.,2019

3. Bacterial Pneumonia in Patients with Cancer: Novel Risk Factors and Management;Wong;Clin. Chest Med.,2017

4. Schuster, M.G., Cleveland, A.A., Dubberke, E.R., Kauffman, C.A., Avery, R.K., Husain, S., Paterson, D.L., Silveira, F.P., Chiller, T.M., and Benedict, K. (2017). Open Forum Infectious Diseases, Oxford University Press.

5. Pneumonia in allogeneic stem cell transplantation recipients: A multicenter prospective study;Espigado;Clin. Transplant.,2011

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3