The Role of Interleukin 6 in Periodontitis and Its Complications-Reference-Cited by-同舟云学术

The Role of Interleukin 6 in Periodontitis and Its Complications

Published:2024-02-10 Issue:4 Volume:25 Page:2146
ISSN:1422-0067
Container-title:International Journal of Molecular Sciences
language:en
Short-container-title:IJMS

Author:

Mazurek-Mochol Małgorzata¹,Bonsmann Tobias¹,Mochol Martyna¹,Poniewierska-Baran Agata²³^ORCID,Pawlik Andrzej³^ORCID

Affiliation:

1. Department of Periodontology, Pomeranian Medical University in Szczecin, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland

2. Institute of Biology, University of Szczecin, Felczaka 3c, 71-412 Szczecin, Poland

3. Department of Physiology, Pomeranian Medical University in Szczecin, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland

Abstract

Interleukin 6 (IL-6) is a pleomorphic pro-inflammatory cytokine that is strongly associated with local as well as systemic inflammatory processes. Its role in physiological and pathogenic processes throughout the human body has been the subject of numerous studies in recent years. Measurements of the IL-6 levels in gingival crevicular fluid (GFC), as well as in serum, can be important diagnostic and prognostic factors in periodontal diseases (PD) and in assessing their impact on a range of related inflammatory diseases. This narrative review explores the significant role of IL-6 in patients with periodontitis and its association with other widespread inflammatory pathologies.

Publisher

MDPI AG

Link

https://www.mdpi.com/1422-0067/25/4/2146/pdf

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