Assessment of Salt, Potassium, and Iodine Intake in the Croatian Adult Population Using 24 h Urinary Collection: The EH-UH 2 Study

Author:

Marinović Glavić Mihaela1ORCID,Bilajac Lovorka123,Bolješić Marta4ORCID,Bubaš Marija56,Capak Krunoslav5,Domislović Marija78,Džakula Aleksandar9,Fuček Mirjana10,Gellineo Lana7,Jelaković Ana17,Josipović Josipa1112,Jukić Tomislav813ORCID,Juraga Denis1ORCID,Pećin Ivan814ORCID,Prelević Vladimir715,Radunović Danilo715ORCID,Reiner Željko1416,Rukavina Tomislav13ORCID,Šušnjara Petar17ORCID,Vasiljev Vanja1ORCID,Vidranski Valentina18,Jelaković Bojan7819

Affiliation:

1. Department of Social Medicine and Epidemiology, Faculty of Medicine, University of Rijeka, 51000 Rijeka, Croatia

2. Department of Public Health, Faculty of Health Studies, University of Rijeka, 51000 Rijeka, Croatia

3. Teaching Institute of Public Health Primorje—Gorski Kotar County, 51000 Rijeka, Croatia

4. Department of Anatomy and Neuroscience, Faculty of Medicine, University of Osijek, 31000 Osijek, Croatia

5. Croatian Institute of Public Health, 10000 Zagreb, Croatia

6. Ministry of Health, 10000 Zagreb, Croatia

7. Department for Nephrology, Hypertension, Dialysis and Transplantation University Hospital Centre, 10000 Zagreb, Croatia

8. School of Medicine, University of Zagreb, 10000 Zagreb, Croatia

9. Department of Social Medicine and Organization of Health Care, Andrija Štampar School of Public Health, University of Zagreb School of Medicine, 10000 Zagreb, Croatia

10. Department of Laboratory Diagnostics, University Hospital Centre Zagreb, 10000 Zagreb, Croatia

11. Department of Nephrology and Dialysis, Sestre Milosrdnice University Hospital Centre, 10000 Zagreb, Croatia

12. School of Medicine, Catholic University of Croatia, 10000 Zagreb, Croatia

13. Department of Oncology and Nuclear Medicine, Sestre Milosrdnice University Hospital Centre, 10000 Zagreb, Croatia

14. Department for Metabolic Diseases, University Hospital Centre Zagreb, 10000 Zagreb, Croatia

15. Clinic for Nephrology, Clinical Centre of Montenegro, 81000 Podgorica, Montenegro

16. Department of Cardiology and Congenital Diseases of Adults, Polish Mother’s Memorial Hospital Research Institute, 93-338 Lodz, Poland

17. Faculty of Kinesiology Osijek, Josip Juraj Strosssmayer, University of Osijek, 31000 Osijek, Croatia

18. Department of Clinical Chemistry, Sestre Milosrdnice University Hospital Centre, 10000 Zagreb, Croatia

19. Croatian Hypertension League, 10000 Zagreb, Croatia

Abstract

Cardiovascular diseases, which are the leading cause of death in Croatia, are linked to the high prevalence of hypertension. Both are associated with high salt intake, which was determined almost two decades ago when Croatian Action on Salt and Health (CRASH) was launched. The main objective of the present study was to evaluate salt, potassium, and iodine intake using a single 24 h urine sample in a random sample of the adult Croatian population and to analyse trends in salt consumption after the CRASH was intensively started. Methods: In this study, we analysed data on 1067 adult participants (mean age 57.12 (SD 13.9), men 35%). Results: Mean salt and potassium intakes were 8.6 g/day (IQR 6.2–11.2) and 2.8 g/day (IQR 2.1–3.5), respectively, with a sodium-to-potassium ratio of 2.6 (IQR 1.8–3.3). We detected a decrease of 17.6% (2 g/day less) in salt consumption compared with our previous salt-mapping study. However, only 13.7% and 8.9% met the WHO salt and potassium recommended targets of 5 g/day and 3.5 g/day, respectively. Salt intake was higher, and potassium ingestion was lower, in rural vs. urban regions and in continental vs. Mediterranean parts of Croatia. Moderate to severe iodine insufficiency was determined in only 3% of the adult participants. Conclusion: In the last fifteen years, salt consumption has been significantly reduced in the Croatian adult population because of the intensive and broad CRASH program. However, salt intake is still too high, and potassium ingestion is too low. Salt reduction programs are the most cost-effective methods of cardiovascular disease prevention and merit greater consideration by the government and health policy makers.

Funder

Croatian Science Foundation research grant

Croatian Society of Hypertension

Croatian Science Foundation program “Young Researchers’ Career Development Project—training of doctoral students”

School of Medicine University of Zagreb

Publisher

MDPI AG

Reference73 articles.

1. World Health Organization (2023). Global Report on Hypertension: The Race against a Silent Killer, World Health Organization. Available online: https://www.who.int/publications/i/item/9789240081062.

2. GBD 2017 Causes of Death Collaborators (2018). Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: A systematic analysis for the Global Burden of Disease Study 2017. Lancet, 392, 1736–1788.

3. Global cardiovascular diseases burden attributable to high sodium intake from 1990 to 2019;Wang;J. Clin. Hypertens,2023

4. Liu, W., Zhou, L., Yin, W., Wang, J., and Zuo, X. (2023). Global, regional, and national burden of chronic kidney disease attributable to high sodium intake from 1990 to 2019. Front. Nutr., 10.

5. Dietary sodium intake and risk of incident type 2 diabetes;Wang;Mayo Clin. Proc.,2023

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