Mortality in Community-Acquired Sepsis and Infections in the Faroe Islands—A Prospective Observational Study

Author:

Todorovic Markovic Marija123,Todorovic Mitic Mirjana4,Ignjatovic Aleksandra5,Gottfredsson Magnús67ORCID,Gaini Shahin238

Affiliation:

1. Department of Cardiology, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark

2. Department of Infectious Diseases, Odense University Hospital, 5000 Odense, Denmark

3. Department of Medicine, Infectious Diseases Division, National Hospital of the Faroe Islands, JC. Svabosgøta 41-49, 100 Torshavn, Faroe Islands

4. Clinic of Oncology, Clinical Centre, 18000 Nis, Serbia

5. Department of Medical Statistics and Informatics, School of Medicine, University of Nis, 18108 Nis, Serbia

6. Department of Infectious Diseases, Landspitali University Hospital, 105 Reykjavik, Iceland

7. Faculty of Medicine, School of Health Sciences, University of Iceland, 101 Reykjavik, Iceland

8. Faculty of Health Sciences, University of the Faroe Islands, 100 Torshavn, Faroe Islands

Abstract

The aim of this study was to collect data and analyze mortality among patients hospitalized with community-acquired infections in the Faroe Islands. A prospective observational study was conducted in the Medical Department of the National Hospital of the Faroe Islands from October 2013 to April 2015. Cumulative all-cause, in-hospital, short-term, intermediate-term and long-term mortality rates were calculated. Kaplan–Meier survival curves comparing infection-free patients with infected patients of all severities and different age groups are presented. A log-rank test was used to compare groups. Mortality hazard ratios were calculated for subgroups using Cox regression multivariable models. There were 1309 patients without infection and 755 patients with infection. There were 51% female and 49% male patients. Mean age was 62.73 ± 19.71. Cumulative all-cause mortality and in-hospital mortality were highest in more severe forms of infection. This pattern remained the same for short-term mortality in the model adjusted for sex and age, while there were no significant differences among the various infection groups in regard to intermediate- or long-term survival after adjustment. Overall and short-term mortality rates were highest among those with severe manifestations of infection and those with infection compared to infection-free patients.

Funder

Research Council Faroe Islands

National Hospital of the Faroe Islands

Publisher

MDPI AG

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