Current Status and Challenges in the Commercial Production of Polyhydroxyalkanoate-Based Bioplastic: A Review

Abstract

The escalating worldwide concerns over the difficult degradation and pollution of plastic and its associated environmental and health risks have amplified the urgent need to develop biodegradable alternatives to traditional plastics. Polyhydroxyalkanoates (PHAs) have emerged as a promising class of biopolymers that offer a sustainable solution. Their commercial success in various applications has highlighted PHAs’ potential to mitigate environmental impact. Critical to the economic feasibility of PHA production is the optimization of downstream processing methods, crucial for scaling operations from pilot to industrial scales. This paper reviews two decades of pilot-scale studies on PHA extraction, emphasizing the advancements and challenges encountered. It also discusses chemical extraction methods applied across different feedstock and microbial strains, highlighting their role in enhancing efficiency and sustainability. This comprehensive review underscores the imperative for advancing PHA technologies, particularly in refining extraction techniques, to facilitate broader adoption in industries seeking environmentally friendly alternatives to conventional plastics.