Abstract
Recently, new high-resolution cadmium–zinc–telluride (CZT) drift strip detectors for room temperature gamma-ray spectroscopic imaging were developed by our group. The CZT detectors equipped with orthogonal anode/cathode collecting strips, drift strips and dedicated pulse processing allow a detection area of 6 × 20 mm2 and excellent room temperature spectroscopic performance (0.82% FWHM at 661.7 keV). In this work, we investigated the potentialities of these detectors for prompt gamma-ray spectroscopy (PGS) in boron neutron capture therapy (BNCT). The detectors, exploiting the measurement of the 478 keV prompt gamma rays emitted by 94% 7Li nuclides from the 10B(n, α)7Li reaction, are very appealing for the development of single-photon emission computed tomography (SPECT) systems and Compton cameras in BNCT. High-resolution gamma-ray spectra from 10B samples under thermal neutrons were measured at the T.R.I.G.A. Mark II research nuclear reactor of the University of Pavia (Italy).
Subject
Electrical and Electronic Engineering,Biochemistry,Instrumentation,Atomic and Molecular Physics, and Optics,Analytical Chemistry
Reference41 articles.
1. Biological effects and therapeutic possibilities of neutrons;Locher;Am. J. Roentgenol. Radium Ther.,1936
2. Some Biological Effects of Nuclear Disintegration Products on Neoplastic Tissue
3. Neutron capture therapy of gliomas using boron-10;Farr;Trans. Am. Neurol. Assoc.,1954
4. Future possibility of neutron capture therapy of malignant tumors by use of low energy neutron from nuclear reactors and other sources;Hatanaka;Gan No Rinsho,1969
5. First BNCT treatment of a skin melanoma in Argentina: dosimetric analysis and clinical outcome
Cited by
19 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献