Abstract
Cancer metastasis is the primary cause of high mortality of cancer patients. Enumeration of circulating tumor cells (CTCs) in the bloodstream is a very important indicator to estimate the therapeutic outcome in various metastatic cancers. The aim of this article is to review recent developments on the CTC isolation technologies in microdevices. Based on the categories of biochemical and biophysical isolation approaches, a literature review and in-depth discussion will be included to provide an overview of this challenging topic. The current excellent developments suggest promising CTC isolation methods in order to establish a precise indicator of the therapeutic outcome of cancer patients.
Subject
Electrical and Electronic Engineering,Mechanical Engineering,Control and Systems Engineering
Reference86 articles.
1. Detection of bone metastasis in nasopharyngeal carcinoma by bone scintigraphy: A retrospective study in perspective of limited resource settings
2. Metastasis from oral cancer: An overview;Noguti;Cancer Genom. Proteom.,2012
3. Cancer Metastasis: Building a Framework
4. Circulating Tumor Cells
5. A case of cancer in which cells similar to those in the tumours were seen in the blood after death;Ashworth;Aust. Med. J.,1869
Cited by
22 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献