Radiomics in Lung Metastases: A Systematic Review

Author:

Gabelloni Michela1,Faggioni Lorenzo2ORCID,Fusco Roberta3,Simonetti Igino4,De Muzio Federica5,Giacobbe Giuliana6,Borgheresi Alessandra78,Bruno Federico910ORCID,Cozzi Diletta1011ORCID,Grassi Francesca12,Scaglione Mariano13,Giovagnoni Andrea78,Barile Antonio14ORCID,Miele Vittorio1011ORCID,Gandolfo Nicoletta15,Granata Vincenza4ORCID

Affiliation:

1. Nuclear Medicine Unit, Department of Translational Research, University of Pisa, 56126 Pisa, Italy

2. Academic Radiology, Department of Translational Research, University of Pisa, 56126 Pisa, Italy

3. Medical Oncology Division, Igea SpA, 80013 Naples, Italy

4. Division of Radiology, Istituto Nazionale Tumori IRCCS Fondazione Pascale—IRCCS di Napoli, 80131 Naples, Italy

5. Department of Medicine and Health Sciences V. Tiberio, University of Molise, 86100 Campobasso, Italy

6. General and Emergency Radiology Department, “Antonio Cardarelli” Hospital, 80131 Naples, Italy

7. Department of Radiology, University Hospital “Azienda Ospedaliera Universitaria delle Marche”, 60126 Ancona, Italy

8. Department of Clinical, Special and Dental Sciences, Università Politecnica delle Marche, 60121 Ancona, Italy

9. Department of Diagnostic Imaging, Area of Cardiovascular and Interventional Imaging, Abruzzo Health Unit 1, 67100 L’Aquila, Italy

10. Italian Society of Medical and Interventional Radiology, SIRM Foundation, 20122 Milan, Italy

11. Department of Emergency Radiology, Careggi University Hospital, 50134 Florence, Italy

12. Department of Precision Medicine, Università degli Studi della Campania “Luigi Vanvitelli”, 80138 Naples, Italy

13. Department of Surgery, Medicine and Pharmacy, University of Sassari, 07100 Sassari, Italy

14. Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, 67100 L’Aquila, Italy

15. Diagnostic Imaging Department, Villa Scassi Hospital-ASL 3, 16149 Genoa, Italy

Abstract

Due to the rich vascularization and lymphatic drainage of the pulmonary tissue, lung metastases (LM) are not uncommon in patients with cancer. Radiomics is an active research field aimed at the extraction of quantitative data from diagnostic images, which can serve as useful imaging biomarkers for a more effective, personalized patient care. Our purpose is to illustrate the current applications, strengths and weaknesses of radiomics for lesion characterization, treatment planning and prognostic assessment in patients with LM, based on a systematic review of the literature.

Publisher

MDPI AG

Subject

Medicine (miscellaneous)

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