Affiliation:
1. Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China
Abstract
Research into bone tissue engineering is increasing with advances in biomaterials. Natural products of plant origin have exciting therapeutic effects through multiple targets. The purpose of this article is to review the outstanding performance of herbal-derived natural products in bone tissue engineering. We have categorized herbal-derived natural products that exert different effects in bone tissue engineering into osteogenic, vascular, chondrogenic, anti-inflammatory and antibacterial. Natural products of plant origin are readily available and can be combined with biomaterials as bioactive molecules to complement each other and provide additional opportunities for bone tissue engineering. Finally, we discuss the challenges and opportunities for the development of plant composite biomaterials for bone tissue engineering and highlight emerging strategies in this field.
Funder
National Key R&D Program of China
National Natural Science Foundation of China
Guangdong Basic and Applied Basic Research Fund
Shenzhen International Collaborative Project
SIAT Innovation Program for Excellent Young Researchers
Subject
Process Chemistry and Technology,Chemical Engineering (miscellaneous),Bioengineering