West Nile Virus in Italy: An Update of the Viral Strains Circulating in the Late 2022 Epidemic Season-Reference-Cited by-同舟云学术

West Nile Virus in Italy: An Update of the Viral Strains Circulating in the Late 2022 Epidemic Season

Published:2024-02-05 Issue:1 Volume:4 Page:49-56
ISSN:2813-0227
Container-title:Zoonotic Diseases
language:en
Short-container-title:Zoonotic Diseases

Author:

Valleriani Fabrizia¹^ORCID,Polci Andrea¹^ORCID,Iapaolo Federica¹^ORCID,Portanti Ottavio¹^ORCID,Pisciella Maura¹^ORCID,Cersini Antonella²^ORCID,Guercio Annalisa³^ORCID,Del Lesto Irene²^ORCID,Curini Valentina¹^ORCID,Mincarelli Luana Fiorella¹^ORCID,Gucciardi Francesca³^ORCID,De Liberato Claudio²,Purpari Giuseppa³^ORCID,Amatori Giorgia¹^ORCID,Morelli Daniela¹,Savini Giovanni¹^ORCID,Monaco Federica¹^ORCID

Affiliation:

1. Istituto Zooprofilattico Sperimentale Abruzzo e Molise “G. Caporale”, 64100 Teramo, Italy

2. Istituto Zooprofilattico Sperimentale Del Lazio e Della Toscana “M. Aleandri”, 00178 Roma, Italy

3. Istituto Zooprofilattico Sperimentale Della Sicilia “A. Mirri”, 97100 Ragusa, Italy

Abstract

West Nile virus (WNV) (Flaviviridae, Flavivirus) infection is a mosquito-borne zoonosis able of causing disease and death in humans and animals. Over the past decade, WNV infections have been a significant public health concern in Europe, and Italy has been among the most affected countries since 2008. The 2022 vector season has been characterized by an intense and early circulation of WNV. This report describes cases of co-circulation of WNV L1 and of WNV L2 occurring at the end of the 2022 vector season in Sicily and Tuscany, regions where no strains had ever been sequenced. The phylogenetic analysis of the detected strains confirmed the peculiar WNV scenario that has characterized the Italian West Nile disease (WND) epidemic since its appearance. The circulation observed in Tuscany was in fact a consequence of the spread of endemic strains to new areas while the Sicilian episodes were linked to new introductions of WNV L1 and L2 strains likely from other European countries.

Funder

Italian Ministry of Health

Publisher

MDPI AG

Link

https://www.mdpi.com/2813-0227/4/1/6/pdf

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