Pleural Mesothelioma: Treatable Traits of a Heterogeneous Disease

Author:

Bertuccio Francesco Rocco12,Agustoni Francesco13,Galli Giulia13,Bortolotto Chandra45ORCID,Saddi Jessica67,Baietto Guido8,Baio Nicola12,Montini Simone12,Putignano Paola12,D’Ambrosio Gioacchino9,Corsico Angelo G.12,Pedrazzoli Paolo13,Stella Giulia Maria12ORCID

Affiliation:

1. Department of Internal Medicine and Medical Therapeutics, University of Pavia Medical School, 27100 Pavia, Italy

2. Cardiothoracic and Vascular Department, Unit of Respiratory Diseases, IRCCS Policlinico San Matteo, 27100 Pavia, Italy

3. Department of Medical Oncology, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy

4. Diagnostic Imaging and Radiotherapy Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy

5. Radiology Institute, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy

6. Department of Oncology, Clinical-Surgical, Unit of Radiation Therapy, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy

7. Department of Radiation Oncology, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy

8. Cardiothoracic and Vascular Department, Unit of Thoracic Surgery, IRCCS Policlinico San Matteo, 27100 Pavia, Italy

9. Pathology Unit, Department of Diagnostical Services and Imaging, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy

Abstract

Pleural mesothelioma is an aggressive disease with diffuse nature, low median survival, and prolonged latency presenting difficulty in prognosis, diagnosis, and treatment. Here, we review all these aspects to underline the progress being made in its investigation and to emphasize how much work remains to be carried out to improve prognosis and treatment.

Publisher

MDPI AG

Subject

Cancer Research,Oncology

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