Preclinical Patient-Derived Culture Models for Personalized Treatment of Pancreatic Cancer: A Dream of the Future or Useful Practice?-Reference-Cited by-同舟云学术

Preclinical Patient-Derived Culture Models for Personalized Treatment of Pancreatic Cancer: A Dream of the Future or Useful Practice?

Published:2023-06-01 Issue:11 Volume:15 Page:3027
ISSN:2072-6694
Container-title:Cancers
language:en
Short-container-title:Cancers

Author:

Braun Rüdiger¹,Ungefroren Hendrik¹²³^ORCID

Affiliation:

1. Department of Surgery, University Medical Center Schleswig-Holstein, Campus Lübeck, 23538 Lübeck, Germany

2. Department of Medicine I, University Medical Center Schleswig-Holstein, Campus Lübeck, 23538 Lübeck, Germany

3. Institute of Pathology, University Medical Center Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany

Abstract

Pancreatic cancer is currently the fourth most common cause of cancer-related deaths and is predicted to be the second leading cause of cancer-related mortality by the year 2030 [...]

Publisher

MDPI AG

Subject

Cancer Research,Oncology

Link

https://www.mdpi.com/2072-6694/15/11/3027/pdf

Reference5 articles.

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2. Frappart, P.O., and Hofmann, T.G. (2020). Pancreatic Ductal Adenocarcinoma (PDAC) Organoids: The Shining Light at the End of the Tunnel for Drug Response Prediction and Personalized Medicine. Cancers, 12.

3. Holokai, L., Chakrabarti, J., Lundy, J., Croagh, D., Adhikary, P., Richards, S.S., Woodson, C., Steele, N., Kuester, R., and Scott, A. (2020). Murine- and Human-Derived Autologous Organoid/Immune Cell Co-Cultures as Pre-Clinical Models of Pancreatic Ductal Adenocarcinoma. Cancers, 12.

4. Braun, R., Lapshyna, O., Eckelmann, S., Honselmann, K., Bolm, L., Ten Winkel, M., Deichmann, S., Schilling, O., Kruse, C., and Keck, T. (2021). Organotypic Slice Cultures as Preclinical Models of Tumor Microenvironment in Primary Pancreatic Cancer and Metastasis. J. Vis. Exp., 172.

5. Weitz, J.R., Tiriac, H., Hurtado de Mendoza, T., Wascher, A., and Lowy, A.M. (2021). Using Organotypic Tissue Slices to Investigate the Microenvironment of Pancreatic Cancer: Pharmacotyping and Beyond. Cancers, 13.