Gynecological Cancer and Venous Thromboembolism: A Narrative Review to Increase Awareness and Improve Risk Assessment and Prevention-Reference-Cited by-同舟云学术

Gynecological Cancer and Venous Thromboembolism: A Narrative Review to Increase Awareness and Improve Risk Assessment and Prevention

Published:2024-05-03 Issue:9 Volume:16 Page:1769
ISSN:2072-6694
Container-title:Cancers
language:en
Short-container-title:Cancers

Author:

Falanga Anna¹²^ORCID,Lorusso Domenica³,Colombo Nicoletta¹⁴,Cormio Gennaro⁵⁶^ORCID,Cosmi Benilde⁷⁸,Scandurra Giuseppa⁹,Zanagnolo Vanna¹⁰,Marietta Marco¹¹

Affiliation:

1. Department of Medicine and Surgery, University of Milan-Bicocca, 20900 Monza, Italy

2. Department of Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, 24127 Bergamo, Italy

3. Fondazione Policlinico Universitario A. Gemelli, Catholic University of Sacred Heart, 00168 Rome, Italy

4. Gynecologic Oncology Program, European Institute of Oncology, IRCCS, 20141 Milan, Italy

5. Gynecologic Oncology Unit, IRCCS Istituto Tumori “Giovanni Paolo II”, 70124 Bari, Italy

6. Department of Interdisciplinary Medicine (DIM), University “A. Moro”, 70124 Bari, Italy

7. Angiology and Blood Coagulation Unit, Department of Medical and Surgical Sciences, University of Bologna, 40126 Bologna, Italy

8. Angiology and Blood Coagulation Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy

9. Unità Operativa Oncologia Medica, Ospedale Cannizzaro di Catania, 95126 Catania, Italy

10. IEO European Institute of Oncology, 20141 Milan, Italy

11. Hematology Unit, Azienda Ospedaliero-Universitaria, 41125 Modena, Italy

Abstract

The prevention and appropriate management of venous thromboembolism in cancer patients is of paramount importance. However, the literature data report an underestimation of this major problem in patients with gynecological cancers, with an inconsistent venous thromboembolism risk assessment and prophylaxis in this patient setting. This narrative review provides a comprehensive overview of the available evidence regarding the management of venous thromboembolism in cancer patients, focusing on the specific context of gynecological tumors, exploring the literature discussing risk factors, risk assessment, and pharmacological prophylaxis. We found that the current understanding and management of venous thromboembolism in gynecological malignancy is largely based on studies on solid cancers in general. Hence, further, larger, and well-designed research in this area is needed.

Publisher

MDPI AG

Link

https://www.mdpi.com/2072-6694/16/9/1769/pdf

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