Author:
De Giovanni ,Nicoletti ,Landuzzi ,Palladini ,Lollini ,Nanni
Abstract
The TS/A cell line was established in 1983 from a spontaneous mammary tumor arisen in an inbred BALB/c female mouse. Its features (heterogeneity, low immunogenicity and metastatic ability) rendered the TS/A cell line suitable as a preclinical model for studies on tumor–host interactions and for gene therapy approaches. The integrated biological profile of TS/A resulting from the review of the literature could be a path towards the description of a precision experimental model of mammary cancer.
Funder
Italian Association for Cancer Research
University of Bologna
Cited by
17 articles.
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