Human Milk—The Biofluid That Nourishes Infants from the First Day of Life

Author:

Lugonja Nikoleta1ORCID,Marinković Vesna2ORCID,Pucarević Mira3ORCID,Miletić Srdjan1ORCID,Stojić Nataša3ORCID,Crnković Dragan4ORCID,Vrvić Miroslav3

Affiliation:

1. Institute of Chemistry, Technology and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade, Njegoševa 12, 11000 Belgrade, Serbia

2. Institute of Neonatology, Kralja Milutina 50, 11000 Belgrade, Serbia

3. Faculty of Environmental Protection, Educons University, Vojvode Putnika 87, 21208 Sremska Kamenica, Serbia

4. City Public Health Institute of Belgrade, Blvd. Despot Stefana 54a, 11108 Belgrade, Serbia

Abstract

Human milk is a biofluid with a unique composition among mammalian milks. Besides this milk’s major components, its bioactive compounds, like hormones, immune factors, and oligosaccharides, are unique and important for infant growth and development. The best form of nutrition for term and preterm infants is the mother’s own milk. However, in the absence of the mother’s own milk, donor milk should be made available. Milk banks support neonatal intensive care units by providing preterm infants with human milk that generally has reasonable nutritive value for this sensitive population. However, neither mother’s own milk nor donor milk has sufficient energy content for the growth of preterm babies, so adequate human milk supplementation is crucial for their progress. Due to the different characteristics of human breast milk, as well as ubiquitous environmental pollutants, such as microplastics, new methods are required for monitoring the quality and characteristics of human milk, which will lay a solid foundation for the further development and progress of human milk research.

Funder

European Union’s Horizon Europe Project GREENLand—Twinning Microplastic-free Environment

Publisher

MDPI AG

Reference157 articles.

1. WHO (2023, August 16). Infants Exclusively Breastfed for the First Six Months of Life (%). Available online: https://www.who.int/data/gho/data/indicators/indicator-details/GHO/infants-exclusively-breastfed-for-the-first-six-months-of-life-(-).

2. World Health Organization (2023, August 16). Protecting, Promoting and Supporting Breastfeeding in Facilities Providing Maternity and Newborn Services. Available online: https://www.who.int/publications/i/item/9789241550086.

3. Department of Economic and Social Affairs, United Nations (2022). World Population Prospects, Department of Economic and Social Affairs.

4. WHO (2023, August 16). Preterm Birth. Available online: https://www.who.int/news-room/fact-sheets/detail/preterm-birth.

5. Binder, C., Baumgartner-Parzer, S., Gard, L.-I., Berger, A., and Thajer, A. (2023). Human Milk Processing and Its Effect on Protein and Leptin Concentrations. Nutrients, 15.

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