Genetic Aspects of Familial Thyroid Cancer

Author:

Morrison Patrick J.1,Atkinson A. Brew2

Affiliation:

1. Regional Medical Genetics Centre, Belfast City Hospital, Belfast, United Kingdom

2. Regional Centre for Endocrinology and Diabetes, Royal Victoria Hospital, Belfast, United Kingdom

Abstract

Learning Objectives Apply the principles of genetics to heritable aspects of thyroid cancer. Explain and discuss presymptomatic gene testing with family members of patients with familial thyroid cancer. Proactively manage patients presenting with a family history of thyroid cancer. This article is available for continuing medical education credit at CME.TheOncologist.com.

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Reference43 articles.

1. Positional cloning of the gene for multiple endocrine neoplasia-type 1;Chandrasekharappa;Science,1997

2. Genetic and clinical analysis in 10 Spanish patients with multiple endocrine neoplasia type 1;Cebrían;Eur J Hum Genet,1999

3. Mutations in the MEN 1 gene in sporadic neuroendocrine tumours of gastroenteropancreatic system;Toliat;Lancet,1997

4. Characterization of mutations in patients with multiple endocrine neoplasia type 1;Bassett;Am J Hum Genet,1998

5. Multiple endocrine neoplasia type 2A: A Northern Ireland and Australian family;Hadden;Henry Ford Hosp Med J,1987

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