TERT Promoter Mutations Are a Major Indicator of Poor Outcome in Differentiated Thyroid Carcinomas

Author:

Melo Miguel123,da Rocha Adriana Gaspar14,Vinagre João15,Batista Rui1,Peixoto Joana1,Tavares Catarina14,Celestino Ricardo16,Almeida Ana15,Salgado Catarina1,Eloy Catarina1,Castro Patrícia1,Prazeres Hugo17,Lima Jorge1,Amaro Teresina8,Lobo Cláudia9,Martins Maria João10,Moura Margarida1112,Cavaco Branca1112,Leite Valeriano111312,Cameselle-Teijeiro José Manuel14,Carrilho Francisco2,Carvalheiro Manuela23,Máximo Valdemar115,Sobrinho-Simões Manuel11516,Soares Paula115

Affiliation:

1. Institute of Molecular Pathology and Immunology of the University of Porto (M.Me., A.G.d.R., J.V., R.B., J.P., C.T., R.C., A.A., C.S., C.E., P.C., H.P., J.L., V.M., M.S.-S., P.S.), 4200-465 Porto, Portugal

2. Departments of Endocrinology, Diabetes, and Metabolism (M.Me., F.C., M.C.), 3000-075 Coimbra, Portugal

3. Unit of Endocrinology (M.Me., M.C.), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal

4. Medical Faculty, University of Porto (A.G.d.R., C.T.), 4200-139 Porto, Portugal

5. Institute of Biomedical Sciences of Abel Salazar, University of Porto (J.V., A.A.), 4050-313 Porto, Portugal

6. School of Allied Health Sciences, ESTSP - Escola Superior de Tecnologia da Saúde do Porto (R.C.), Polytechnic of Porto, 4400-330 Vila Nova de Gaia, Portugal

7. Portuguese Institute of Oncology (H.P.), Coimbra Center, 3000-075 Coimbra, Portugal

8. Department of Pathology (T.A.), Hospital Pedro Hispano, 4464-513 Matosinhos, Portugal

9. Department of Pathology (C.L.), Portuguese Institute of Oncology, Porto Center, 4200-072 Porto, Portugal

10. Pathology (M.J.M.), University and Hospital Center of Coimbra, 3000-075 Coimbra, Portugal

11. Center for Investigation of Molecular Pathobiology (M.Mo., B.C., V.L.), 1099-023 Lisbon, Portugal

12. Center for the Study of Chronic Diseases (M.Mo., B.C., V.L.), Faculty of Medical Sciences, University of Lisbon, 1099-085 Lisbon, Portugal

13. Department of Endocrinology (V.L.), Portuguese Institute of Oncology, Lisbon Center, 1099-023 Lisbon, Portugal

14. Department of Pathology (J.M.C.-T.), Clinical University Hospital, Servicio Gallego de Salud - SERGAS, Medical Faculty, University of Santiago de Compostela, 15705 Santiago de Compostela, Spain

15. Department of Pathology and Oncology, Medical Faculty, University of Porto (J.L., V.M., M.S.-S., P.S.), 4200-139 Porto, Portugal

16. Department of Pathology (M.S.-S.), Hospital S. João, 4200-319 Porto, Portugal

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

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