Sex-Dimorphic and Sex Hormone–Dependent Role of Steroid Sulfatase in Adipose Inflammation and Energy Homeostasis

Author:

Bi Yuhan12,Jiang Mengxi12,Guo Weiwei12,Guan Xiudong3,Xu Meishu12,Ren Songrong12,Yang Da12,Gaikwad Nilesh W4,Selcer Kyle W5,Xie Wen126

Affiliation:

1. Center for Pharmacogenetics, University of Pittsburgh, Pittsburgh, Pennsylvania

2. Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania

3. Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

4. Gaikwad Steroidomics Laboratory, Davis, California

5. Department of Biological Sciences, Duquesne University, Pittsburgh, Pennsylvania

6. Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania

Funder

National Institutes of Health

Publisher

The Endocrine Society

Subject

Endocrinology

Reference52 articles.

1. Endogenous sex hormones and the development of type 2 diabetes in older men and women: the Rancho Bernardo study;Oh;Diabetes Care,2002

2. The role of androgens in metabolism, obesity, and diabetes in males and females;Navarro;Obesity (Silver Spring),2015

3. The emergence of the metabolic syndrome with menopause;Carr;J Clin Endocrinol Metab,2003

4. Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man;Smith;N Engl J Med,1994

5. Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens;Morishima;J Clin Endocrinol Metab,1995

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