A Novel Androgen Receptor Amino Terminal Region Reveals Two Classes of Amino/Carboxyl Interaction-Deficient Variants with Divergent Capacity to Activate Responsive Sites in Chromatin-Reference-Cited by-同舟云学术

A Novel Androgen Receptor Amino Terminal Region Reveals Two Classes of Amino/Carboxyl Interaction-Deficient Variants with Divergent Capacity to Activate Responsive Sites in Chromatin

Published:2009-03-12 Issue:6 Volume:150 Page:2674-2682
ISSN:0013-7227
Container-title:Endocrinology
language:en
Short-container-title:

Author:

Need Eleanor F.¹²,Scher Howard I.³,Peters Amelia A.²,Moore Nicole L.²,Cheong Albert²,Ryan Charles J.⁴,Wittert Gary A.⁵,Marshall Villis R.¹,Tilley Wayne D.²,Buchanan Grant¹²

Affiliation:

1. Molecular Ageing Laboratory (E.F.N., V.R.M., G.B.), Adelaide 5005, Australia

2. Freemasons Foundation Centre for Mens Health, Dame Roma Mitchell Cancer Research Laboratories (E.F.N., A.A.P., N.L.M., A.C., W.D.T., G.B.), Adelaide 5005, Australia

3. Genitourinary Oncology Service (H.I.S.), Division of Solid Tumor Oncology, Memorial Sloan-Kettering Cancer Center, Joan and Sanford I. Weill College of Medicine, New York, New York 10021

4. The Urologic Oncology Program (C.J.R.), Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California 94143

5. University of Adelaide/Hanson Institute, and University of Adelaide, School of Medicine and Royal Adelaide Hospital (G.A.W.), Adelaide 5005, Australia

Publisher

The Endocrine Society

Subject

Endocrinology

Link

http://academic.oup.com/endo/article-pdf/150/6/2674/9005243/endo2674.pdf

Reference50 articles.

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2. Functional domains of the human androgen receptor.;Jenster;J Steroid Biochem Mol Biol,1992

3. Structural basis of androgen receptor binding to selective androgen response elements.;Shaffer;Proc Natl Acad Sci USA,2004

4. A signature motif in transcriptional co-activators mediates binding to nuclear receptors.;Heery;Nature,1997

5. Natural disordered sequences in the amino terminal domain of nuclear receptors: lessons from the androgen and glucocorticoid receptors;McEwan;Nucl Recept Signal,2007

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