Regulation of P450c17 Expression in the Early Embryo Depends on GATA Factors

Author:

Shi Yimin1,Schonemann Marcus D.1,Mellon Synthia H.1

Affiliation:

1. Department of Obstetrics, Gynecology, and Reproductive Science, The Center for Reproductive Sciences, University of California, San Francisco, San Francisco, California 94143

Publisher

The Endocrine Society

Subject

Endocrinology

Reference94 articles.

1. Molecular modeling of human P450c17 (17α-hydroxylase/17,20-lyase): insights into reaction mechanisms and effects of mutations.;Auchus;Mol Endocrinol,1999

2. The regulation of 17,20 lyase activity.;Miller;Steroids,1997

3. Cytochrome b5 augments the 17,20-lyase activity of human P450c17 without direct electron transfer.;Auchus;J Biol Chem,1998

4. Biochemical differences between rat and human cytochrome P450c17 support the different steroidogenic needs of these two species.;Brock;Biochemistry,1999

5. 5α-Reduced C21 steroids are substrates for human cytochrome P450c17.;Gupta;Arch Biochem Biophys,2003

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