Mitochondria of Human Adrenal Cortex Have Tubular Cristae with Bulbous Tips

Author:

Riva Alessandro1,Loffredo Felice1,Uccheddu Alessandro2,Riva Francesca Testa1,Tandler Bernard3

Affiliation:

1. Departments of Cytomorphology (A.R., F.L., F.T.R.), Italy;

2. Surgery (A.U.), University of Cagliari, Italy;

3. Department of Veterans Affairs Medical Center, Geriatric Research Education and Clinical Center (B.T.), Cleveland, Ohio

Abstract

By taking advantage of a modified osmium maceration technique, we have been able to examine by high resolution scanning electron microscopy (HRSEM) the interior of human adrenocortical mitochondria from which all soluble material has been extracted. The so-called vesicles apparent in thin sections examined by transmission electron microscopy actually are finger-like cristae as determined by HRSEM. These digitiform cristae have a segmented appearance and a bulbous tip. The segmented form of the cristae may have important metabolic implications.

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

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