Cultured Muscle Cells from Insulin-Resistant Type 2 Diabetes Patients Have Impaired Insulin, but Normal 5-Amino-4-Imidazolecarboxamide Riboside-Stimulated, Glucose Uptake
Author:
Affiliation:
1. School of Clinical Medical Sciences (E.A.M., M.W.), Newcastle upon Tyne, United Kingdom NE2 4HH
2. School of Cell and Molecular Biosciences (R.H., S.J.Y.), University of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom NE2 4HH
Publisher
The Endocrine Society
Subject
Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism
Link
http://academic.oup.com/jcem/article-pdf/89/7/3440/10744198/jcem3440.pdf
Reference43 articles.
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3. Insulin action and glucose metabolism in nondiabetic control and NIDDM subjects. Comparison using human skeletal muscle cell cultures.;Henry;Diabetes,1995
4. Impaired muscle glycogen synthase in type 2 diabetes is associated with diminished phosphatidylinositol 3-kinase activation.;Nikoulina;J Clin Endocrinol Metab,2001
5. The diabetic phenotype is conserved in myotubes established from diabetic subjects: evidence for primary defects in glucose transport and glycogen synthase activity.;Gaster;Diabetes,2002
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