An Examination of How Different Mutations at Arginine 855 of the Androgen Receptor Result in Different Androgen Insensitivity Phenotypes

Author:

Elhaji Youssef A.12,Hui Wu Jian13,Gottlieb Bruce1,Beitel Lenore K.14,Alvarado Carlos1,Batist Gerald13,Trifiro Mark A.124

Affiliation:

1. Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital (Y.A.E., J.H.W., B.G., L.K.B., C.A., G.B., M.A.T.), Quebec, Canada H3T 1E2

2. Departments of Human Genetics (Y.A.E., M.A.T.), Quebec, Canada H3T 1E2

3. Oncology (J.H.W., G.B.), McGill University, Montreal, Quebec, Canada H3T 1E2

4. Medicine (M.A.T., L.K.B.), Quebec, Canada H3T 1E2

Publisher

The Endocrine Society

Subject

Endocrinology,Molecular Biology,General Medicine

Reference57 articles.

1. A ligand-dependent bipartite nuclear targeting signal in the human androgen receptor. Requirement for the DNA-binding domain and modulation by NH2-terminal and carboxyl-terminal sequences.;Zhou;J Biol Chem,1994

2. Androgen receptor defects: historical, clinical, and molecular perspectives.;Quigley;Endocr Rev,1995

3. Androgen insensitivity.;Gottlieb;Am J Med Genet,1999

4. Update of the androgen receptor gene mutations database.;Gottlieb;Hum Mutat,1999

5. Genotype versus phenotype in families with androgen insensitivity syndrome.;Boehmer;J Clin Endocrinol Metab [Erratum (2002) 87:3109],2001

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