1. Division of Endocrinology, Diabetes & Metabolism, Department of Medicine and Institute for Diabetes, Obesity & Metabolism, University of Pennsylvania Perelman School of Medicine , Philadelphia, PA 19104 , USA
2. Division of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia and Department of Pediatrics, University of Pennsylvania Perelman School of Medicine , Philadelphia, PA 19104 , USA
3. Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Pennsylvania Perelman School of Medicine , Philadelphia, PA 19104 , USA
4. New Bolton Center, University of Pennsylvania School of Veterinary Medicine , Kennett Square, PA 19348 , USA
5. Department of Biostatistics, University of Pennsylvania Perelman School of Medicine , Philadelphia, PA 19104 , USA
6. Division of Allergy and Pulmonary Medicine, Department of Pediatrics, Washington University School of Medicine , St. Louis, MO 63110 , USA
7. Division of Endocrinology and Diabetes, Children's Hospital of Philadelphia and Department of Pediatrics, University of Pennsylvania Perelman School of Medicine , Philadelphia, PA 19104 , USA