High-Dose Estrogen and Clinical Selective Estrogen Receptor Modulators Induce Growth Arrest, p21, and p53 in Primate Ovarian Surface Epithelial Cells

Author:

Wright Jay W.1,Stouffer Richard L.12,Rodland Karin D.3

Affiliation:

1. Division of Reproductive Sciences (J.W.W., R.L.S.), Oregon National Primate Research Center, Beaverton, Oregon 97006;

2. Department of Physiology and Pharmacology (R.L.S.), Oregon Health Sciences University, Portland, Oregon 97201;

3. Molecular BioSciences Department (K.D.R.), Pacific Northwest National Laboratory, Richland, Washington 99352

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference61 articles.

1. Ovarian surface epithelium and human ovarian cancer.;Dietl;Gynecol Obstet Invest,1993

2. Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2.;King;Science,2003

3. Incessant ovulation—a factor in ovarian neoplasia?;Fathalla;Lancet,1971

4. Determinants of ovarian cancer risk. II. Inferences regarding pathogenesis.;Cramer;J Natl Cancer Inst,1983

5. Reproductive hormones and cancer: ovarian and colon cancer.;Burkman;Obstet Gynecol Clin North Am,2002

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