Primary Adrenal Leiomyosarcoma: Clinical, Radiological, and Histopathological Characteristics

Author:

Jabarkhel Fatema1,Puttonen Henri2,Hansson Lina3,Muth Andreas4ORCID,Ragnarsson Oskar1ORCID

Affiliation:

1. Department of Internal Medicine and Clinical Nutrition, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg and The Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden

2. Department of Pathology, Sahlgrenska University Hospital, Gothenburg, Sweden

3. Department of Oncology, Sahlgrenska University Hospital, Gothenburg, Sweden

4. Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden

Abstract

Abstract Primary adrenal leiomyosarcoma (PAL) is a rare, high-grade proliferating mesenchymal tumor with a considerable risk of metastasis, deriving from the smooth muscle wall of a central adrenal vein, or its tributaries. Roughly 40 patients with PAL have been reported in the literature. Herein, we present 3 patients with incidentally discovered PAL, along with an overview of the current knowledge on the clinical, radiological, and histopathological characteristics of PAL.

Publisher

The Endocrine Society

Subject

Endocrinology, Diabetes and Metabolism

Reference43 articles.

1. Primary adrenal leiomyosarcoma: a case report and review of literature;Zhou;Int J Clin Exp Pathol.,2015

2. Primary leiomyosarcoma of adrenal gland. Case report with immunohistochemical and ultrastructural study;Lack;Am J Surg Pathol.,1991

3. Leiomyosarcoma of the adrenal gland and its angiographic features: a case report;Choi;J Surg Oncol.,1981

4. Primary adrenal leiomyosarcoma in an arab male: a rare case report with immunohistochemistry study;Nagaraj;Case Rep Surg.,2015

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