1. The Family Federation of Finland (T.L.B., J.M.M., O.H., R.S., D.A), FIN-00100 Helsinki, Finland
2. the Department of Medicine, Divisions of Internal Medicine (M.L., T.T.), Helsinki, Finland
3. the Department of Endocrinology, Lund University (T.T.), Lund, Sweden
4. Obstetrics and Gynecology (C.-G.N.), Helsinki University Central Hospital, Helsinki, Finland