Different Polymorphisms of the Mineralocorticoid Receptor Gene Are Associated with either Glucocorticoid or Mineralocorticoid Levels in Hypertension

Author:

Sun Bei1,Chamarthi Bindu1,Williams Jonathan S.1,Krug Alexander W.1,Lasky-Su Jessica2,Raby Benjamin A.2,Hopkins Paul N.3,Jeunemaitre Xavier4,Ferri Claudio5,Williams Gordon H.1

Affiliation:

1. Division of Endocrinology, Diabetes, and Hypertension (B.S., B.C., J.S.W., A.W.K., G.H.W.), Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115

2. Channing Laboratory (J.L.-S., B.A.R.), Brigham and Women's Hospital, Boston, Massachusetts 02115

3. Cardiovascular Genetics Research (P.N.H.), Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah 84132

4. Centre d'Investigation Clinique (X.J.), Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche en Santé 970, Université Paris Descartes, 75014 France; Paris, France

5. Department of Internal Medicine and Public Health (C.F.), University of L'Aquila, 67100 L'Aquila, Italy

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference20 articles.

1. The mineralocorticoid receptor: insights into its molecular and (patho)physiological biology.;Viengchareun;Nucl Recept Signal,2007

2. Aldosterone and mineralocorticoid receptors in the cardiovascular system.;Funder;Prog Cardiovasc Dis,2010

3. Aldosterone in heart disease.;Mihailidou;Curr Hypertens Rep,2012

4. The coming out of the brain mineralocorticoid receptor.;Joëls;Trends Neurosci,2008

5. Activating mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy.;Geller;Science,2000

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