A Case of Refractory Bullous Pemphigoid Complicated by Atopic Dermatitis Successfully Treated with Dupilumab
Author:
Affiliation:
1. Department of Dermatology, Yamaguchi University Graduate School of Medicine
2. Department of Dermatology, Yamaguchi Red Cross Hospital
Publisher
Western Japan Division of JDA
Link
https://www.jstage.jst.go.jp/article/nishinihonhifu/86/1/86_26/_pdf
Reference8 articles.
1. 1) 氏家英之, 岩田浩明, 山上 淳ほか:類天疱瘡 (後天性表皮水疱症を含む) 診療ガイドライン. 日皮会誌, 2017;127:1483-1521.
2. 2) Liu Z, Giudice GJ, Swartz SJ et al : The role of complement in experimental bullous pemphigoid, J Clin Invest, 1995 ; 95 : 1539-1544.
3. 3) Ujiie H, Sasaoka T, Izumi K et al : Bullous pemphigoid autoantibodies directly induce blister formation without complement activation. J Immunol, 2014 ; 193 : 4415-4428.
4. 4) Teraki Y, Hotta T, Shiohara T : Skin-Homing Interleukin-4 and -13-Producing Cells Contribute to Bullous Pemphigoid : Remission of Disease is Associated with Increased Frequency of Interleukin-10-Producing Cells. J Invest Dermatol, 2001 ; 117 : 1097-1102.
5. 5) Takamura S, Teraki Y : Treatment of bullous pemphigoid with dupilumab : Dupilumab exerts its effect by primarily suppressing T-helper 2 cytokines. J Dermatol, 2022 ; 49 : 845-850.
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