Separation and Determination of Triclosan and Bisphenol A in Water, Beverage, and Urine Samples by Dispersive Liquid–Liquid Microextraction Combined with Capillary Zone Electrophoresis–UV Detection

Abstract

Abstract Dispersive liquid–liquid microextraction combined with capillary zone electrophoresis–UV detection was developed for analyzing triclosan (TCS) and bisphenol A (BPA) in water, beverage, and urine samples. The factors influencing microextraction efficiencies, such as the kind and volume of extraction and dispersive solvent, the extraction time, and the salt effect, were optimized. A background electrolyte composed of 8 mM sodium tetraborate at pH 9.8 was used as the running buffer. Detection was performed at 214 nm. Under the optimum conditions (sample volume, 5.0 mL; extraction solvent, tetrachloroethane, 22.0 μL; dispersive solvent, tetrahydrofuran, 1.0 mL; extraction time, fewer than 5 s; and without salt addition), the enrichment factors were 110.2 and 82.0 for TCS and BPA, respectively. The linear range was 0.02–2 μg/mL with correlation coefficients of 0.9966–0.9969. LODs were in the range of 4.0–8.0 ng/mL. The environmental water, beverage, and urine samples (at spiking levels of 0.1 and 0.4 μg/mL) were successfully analyzed by the proposed method; the recoveries compared to previous methods were in the range of 81.2–103.3%. As a result, this method can be successfully applied for the rapid and convenient determination of TCS and BPA in water, beverage, and urine samples.