Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review

Author:

Soleimani Vahid12,Delghandi Parisa Sadat12,Moallem Seyed Adel345,Karimi Gholamreza16ORCID

Affiliation:

1. School of PharmacyMashhad University of Medical Sciences Mashhad Iran

2. Student Research CommitteeMashhad University of Medical Sciences Mashhad Iran

3. Department of Pharmacology and Toxicology, Faculty of PharmacyUniversity of Ahl Al Bayt Karbala Iraq

4. Department of Pharmacodynamics and Toxicology, School of PharmacyMashhad University ofMedical Sciences Mashhad Iran

5. Department of Pharmacology and Toxicology, Faculty of PharmacyAlzahraa University Karbala Iraq

6. Pharmaceutical Research Center, Institute of Pharmaceutical TechnologyMashhad University of Medical Sciences Mashhad Iran

Funder

Mashhad University of Medical Sciences

Publisher

Wiley

Subject

Pharmacology

Reference92 articles.

1. Milk thistle in liver diseases: past, present, future

2. Anticancer potential of silymarin: From bench to bed side;Agarwal R.;Anticancer Research,2006

3. Effect of silymarin plus vitamin E in patients with non‐alcoholic fatty liver disease. A randomized clinical pilot study;Aller R.;European Review for Medical and Pharmacological Sciences,2015

4. In vivo anticlastogenic effect of silymarin from milk thistle Silybum marianum L.

5. The Impact of Silymarin on Improvement of Hepatic Abnormalities in Patients with Severe Preeclampsia: A Randomized Clinical Trial

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