Atrial septal interventions during and after hybrid stage I palliation of hypoplastic left heart syndrome

Abstract

AbstractBackgroundHybrid stage I palliation (HS1P) is an alternative approach for initial palliation in hypoplastic left heart syndrome (HLHS) patients. Unlike surgical stage I palliation where atrial septectomy is routinely performed, atrial septal intervention (ASI) during HS1P is variable. In this study, we described our experience with ASI in single ventricle (SV) patients who underwent HS1P and identified factors associated with need for ASI after HS1P.MethodsData were retrospectively collected for all HLHS patients who underwent HS1P at our center over the past 12 years. We evaluated ASIs performed during the HS1P (intra‐HS1P ASI) and ASIs performed during the period from HS1P to the subsequent surgical stage, either interval Norwood stage I or comprehensive stage II (post‐HS1P ASI). Patient factors and procedural data were compared to identify factors associated with undergoing post‐HS1P ASI and the impact of ASI on patient outcomes was evaluated.ResultsOf 50 SV patients included, 23 (46%) underwent intra‐HS1P ASI and 26 (52%) underwent post‐HS1P ASI. Need for post‐HS1P ASI was lower among patients who had an intra‐HS1P ASI as compared to those who did not (30% vs. 70%; p = 0.005). There were no significant differences in short or Midterm outcomes between patients who underwent intra‐HS1P ASI or post‐HS1P ASI and their counterparts.ConclusionsASI is common both during and after HS1P but is generally well tolerated and type of ASI does not significantly impact overall patient outcomes. Our findings suggest that the current approach of individualizing management of ASI in the HS1P population is effective and safe.