Transgenic HepaRG cells expressing CYP2D6 as an improved model of primary human hepatocytes-Reference-Cited by-同舟云学术

Transgenic HepaRG cells expressing CYP2D6 as an improved model of primary human hepatocytes

Published:2022-02-17 Issue:2 Volume:10 Page:
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacology Res & Perspec

Author:

Okuyama Shota¹,Mine Akari¹,Nakamura Teppei¹,Ohasi Yusuke¹,Seto Mayuko¹,Tada Masako¹^ORCID

Affiliation:

1. Stem Cells & Reprogramming Laboratory Department of Biology Faculty of Science Toho University Funabashi Chiba Japan

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.939

Reference12 articles.

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2. Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells

3. Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins

4. Unjustified prescribing of CYP2D6 inhibiting SSRIs in women treated with tamoxifen

5. Common CYP2D6 polymorphisms affecting alternative splicing and transcription: long-range haplotypes with two regulatory variants modulate CYP2D6 activity

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