Application of the Nested Enzyme‐Within‐Enterocyte (NEWE) Turnover Model for Predicting the Time Course of Pharmacodynamic Effects-Reference-Cited by-同舟云学术

Application of the Nested Enzyme‐Within‐Enterocyte (NEWE) Turnover Model for Predicting the Time Course of Pharmacodynamic Effects

Published:2020-09-28 Issue:11 Volume:9 Page:617-627
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT Pharmacometrics Syst. Pharmacol.

Author:

Takita Hiroyuki¹²^ORCID,Darwich Adam S.¹³^ORCID,Ahmad Amais¹^ORCID,Rostami‐Hodjegan Amin¹⁴^ORCID

Affiliation:

1. Centre for Applied Pharmacokinetics Research University of Manchester Manchester UK

2. Laboratory for Safety Assessment and ADME Pharmaceuticals Research Center Asahi Kasei Pharma Corporation Shizuoka Japan

3. Logistics and Informatics in Health Care School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH) KTH Royal Institute of Technology Stockholm Sweden

4. Simcyp Division Certara UK Sheffield UK

Funder

Asahi Kasei Pharma Corporation

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12557

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