Molecular dynamics simulations indicate that tyrosineB10 limits motions of distal histidine to regulate CO binding in soybean leghemoglobin

Author:

Sharma Smriti1,Kumar Amit2,Kundu Suman2,Bandyopadhyay Pradipta1

Affiliation:

1. School of Computational and Integrative Sciences, Jawaharlal Nehru University; New Delhi 110067 India

2. Department of Biochemistry; University of Delhi South Campus; New Delhi 110021 India

Funder

DBT, Government of India (to S.S.), CSIR, Government of India (to A.K.), DBT (Basic Research Grant, 2008), UGC (SAP Programme), Delhi University (R&D and DST-PURSE Programme)

Publisher

Wiley

Subject

Molecular Biology,Biochemistry,Structural Biology

Reference81 articles.

1. Hypoxic survival requires a 2-on-2 hemoglobin in a process involving nitric oxide;Hemschemeier;Proc Natl Acad Sci USA,2013

2. Truncated hemoglobins: a new class of globins with novel structure and function;Kumar;J Proteins Proteomics,2013

3. Androglobin: a chimeric globin in metazoans that is preferentially expressed in mammalian testes;Hoogewijs;Mol Biol Evol,2012

4. An evaluation of potential intrinsically disordered and amyloidogenic regions in hemoglobins;Basireddy;J Proteins Proteomics,2013

5. Androglobin knockdown inhibits growth of glioma cell lines;Huang;Int J Clin Exp Pathol,2014

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