Structural integrity of the ribonuclease H domain in HIV-1 reverse transcriptase

Author:

Slack Ryan L.1,Spiriti Justin2,Ahn Jinwoo1,Parniak Michael A.3,Zuckerman Daniel M.2,Ishima Rieko1

Affiliation:

1. Department of Structural Biology; University of Pittsburgh School of Medicine; Pittsburgh Pennsylvania 15260

2. Department of Computational and Systems Biology; University of Pittsburgh School of Medicine; Pittsburgh Pennsylvania 15260

3. Department of Microbiology and Molecular Genetics; University of Pittsburgh School of Medicine; Pittsburgh Pennsylvania 15260

Funder

National Institutes of Health

National Science Foundation

Publisher

Wiley

Subject

Molecular Biology,Biochemistry,Structural Biology

Reference65 articles.

1. Purification and characterization of heterodimeric human immunodeficiency virus type 1 (HIV-1) reverse transcriptase produced by in vitro processing of p66 with recombinant HIV-1 protease;Chattopadhyay;J Biol Chem,1992

2. Human immunodeficiency virus type 1 (HIV-1) recombinant reverse transcriptase. Asymmetry in p66 subunits of the p66/p66 homodimer;Sharma;FEBS Lett,1994

3. The retroviral enzymes;Katz;Ann Rev Biochem,1994

4. Dimerization kinetics of HIV-1 and HIV-2 reverse transcriptase: a two step process;Divita;J Mol Biol,1995

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