Odanacatib in the treatment of postmenopausal women with low bone mineral density: Three-year continued therapy and resolution of effect

Author:

Eisman John A,Bone Henry G,Hosking David J,McClung Michael R,Reid Ian R,Rizzoli Rene,Resch Heinrich,Verbruggen Nadia,Hustad Carolyn M,DaSilva Carolyn,Petrovic Romana,Santora Arthur C,Ince B Avery,Lombardi Antonio

Publisher

Wiley

Subject

Orthopedics and Sports Medicine,Endocrinology, Diabetes and Metabolism

Reference26 articles.

1. National Osteoporosis Foundation http://nof.org/advocacy/prevalence/index.htm

2. Cathepsin K inhibitors: a novel target for osteoporosis therapy;Stoch;Clin Pharmacol Ther.,2008

3. Effect of one year treatment with the cathepsin-K inhibitor, balicatib, on bone mineral density (BMD) in postmenopausal women with osteopenia/osteoporosis;Adami;J Bone Miner Res.,2006

4. Effect of three month treatment with the cathepsin-K inhibitor, balicatib, on biochemical markers of bone turnover in postmenopausal women: evidence for uncoupling of bone resorption and bone formation;Papanastasiou;J Bone Miner Res.,2006

5. A highly potent inhibitor of cathepsin K (relacatib) reduces biomarkers of bone resorption both in vitro and in an acute model of elevated bone turnover in vivo in monkeys;Kumar;Bone.,2007

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