Deep Generative Medical Image Harmonization for Improving Cross‐Site Generalization in Deep Learning Predictors

Author:

Bashyam Vishnu M.1ORCID,Doshi Jimit1,Erus Guray1,Srinivasan Dhivya1,Abdulkadir Ahmed1,Singh Ashish1,Habes Mohamad2,Fan Yong1,Masters Colin L.3,Maruff Paul3,Zhuo Chuanjun45,Völzke Henry67,Johnson Sterling C.8,Fripp Jurgen9,Koutsouleris Nikolaos10,Satterthwaite Theodore D.111,Wolf Daniel H.11,Gur Raquel E.1112,Gur Ruben C.1112,Morris John C.13,Albert Marilyn S.14,Grabe Hans J.1516,Resnick Susan M.17,Bryan Nick R.18,Wittfeld Katharina1516,Bülow Robin19,Wolk David A.20,Shou Haochang21,Nasrallah Ilya M.12,Davatzikos Christos1,

Affiliation:

1. Artificial Intelligence in Biomedical Imaging Lab University of Pennsylvania Philadelphia Pennsylvania USA

2. Biggs Alzheimer's Institute University of Texas San Antonio Health Science Center San Antonio Texas USA

3. Florey Institute of Neuroscience and Mental Health University of Melbourne Melbourne Victoria Australia

4. Tianjin Mental Health Center Nankai University Affiliated Tianjin Anding Hospital Tianjin China

5. Department of Psychiatry Tianjin Medical University Tianjin China

6. Institute for Community Medicine University Medicine Greifswald Greifswald Germany

7. German Centre for Cardiovascular Research Partner Site Greifswald Greifswald Germany

8. Wisconsin Alzheimer's Institute University of Wisconsin School of Medicine and Public Health Madison Wisconsin USA

9. CSIRO Health and Biosecurity Australian e‐Health Research Centre CSIRO Brisbane Queensland Australia

10. Department of Psychiatry and Psychotherapy Ludwig Maximilian University of Munich Munich Germany

11. Department of Psychiatry University of Pennsylvania Philadelphia Pennsylvania USA

12. Department of Radiology University of Pennsylvania Philadelphia Pennsylvania USA

13. Department of Neurology Washington University in St. Louis St. Louis Missouri USA

14. Department of Neurology Johns Hopkins University School of Medicine Baltimore Maryland USA

15. Department of Psychiatry and Psychotherapy University Medicine Greifswald Greifswald Germany

16. German Center for Neurodegenerative Diseases (DZNE) Site Rostock/Greifswald Greifswald Germany

17. Laboratory of Behavioral Neuroscience National Institute on Aging Baltimore Maryland USA

18. Department of Diagnostic Medicine University of Texas at Austin Austin Texas USA

19. Institute of Diagnostic Radiology and Neuroradiology University Medicine Greifswald Greifswald Germany

20. Department of Neurology University of Pennsylvania Philadelphia Pennsylvania USA

21. Department of Biostatistics, Epidemiology and Informatics University of Pennsylvania Philadelphia Pennsylvania USA

Funder

National Institute on Aging

National Institutes of Health

Siemens Healthineers

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Bundesministerium für Bildung und Forschung

Publisher

Wiley

Subject

Radiology, Nuclear Medicine and imaging

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