Affiliation:
1. Flexible Electronics (IFE Future Technologies) Xiamen University Xiamen 361005 China
2. Future Display Institute in Xiamen Xiamen 361005 China
3. School of Pharmacy Wannan Medical College Wuhu 241002 China
4. Technical Center of Xiamen Customs Xiamen 361001 China
Abstract
AbstractFluorophores are considered powerful tools for not only enabling the visualization of cell structures, substructures, and biological processes, but also making for the quantitative and qualitative measurement of various analytes in living systems. However, most fluorophores do not meet the diverse requirements for biological applications in terms of their photophysical and biological properties. Hybridization is an important strategy in molecular engineering that provides fluorophores with complementarity and multifunctionality. This review summarizes the basic strategies of hybridization with four classes of fluorophores, including xanthene, cyanine, coumarin, and BODIPY with a focus on their structure‐property relationship (SPR) and biological applications. This review aims to provide rational hybrid ideas for expanding the reservoir of knowledge regarding fluorophores and promoting the development of newly produced fluorophores for applications in the field of life sciences.
Funder
National Natural Science Foundation of China
Fundamental Research Funds for the Central Universities
Subject
General Chemistry,Catalysis,Organic Chemistry