SAR Studies of the Leupyrrins: Design and Total Synthesis of Highly Potent Simplified Leupylogs-Reference-Cited by-同舟云学术

SAR Studies of the Leupyrrins: Design and Total Synthesis of Highly Potent Simplified Leupylogs

Published:2020-10-15 Issue:66 Volume:26 Page:15074-15078
ISSN:0947-6539
Container-title:Chemistry – A European Journal
language:en
Short-container-title:Chem. Eur. J.

Author:

Wosniok Paul R.¹²,Knopf Christopher¹³,Dreisigacker Sandra¹⁴,Orozco‐Rodriguez J. Manuel⁵,Hinkelmann Bettina⁵,Mueller Peter P.⁵,Brönstrup Mark⁵,Menche Dirk¹^ORCID

Affiliation:

1. Kekulé-Institut für Organische Chemie und Biochemie Universität Bonn Gerhard-Domagk-Str. 1 53121 Bonn Germany

2. Current address: Eurofins Umwelt West GmbH Wesseling, Vorgebirgsstrasse 20, 50389 Wesseling, Germany

3. Current address: Eurofins Umwelt West GmbH Wesseling, Eurofins Genomics Europe Synthesis GmbH, Anzinger Str. 7a, 85560 Ebersberg, Germany

4. Current address: HWI pharma services GmbH Rheinzaberner Straße 8 76761 Ruelzheim Germany

5. Helmholtz Centre for Infection Research Inhoffenstraße 7 38124 Braunschweig Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/chem.202002622

Reference33 articles.

1. The Leupyrrins: A Structurally Unique Family of Secondary Metabolites from the Myxobacterium Sorangium cellulosum#

2. Identification of myxobacteria-derived HIV inhibitors by a high-throughput two-step infectivity assay

3. Stereochemical Determination of the Leupyrrins and Total Synthesis of Leupyrrin A1

4. Total Synthesis of Leupyrrin B1: A Potent Inhibitor of Human Leukocyte Elastase

5. Total Synthesis of Leupyrrins A1and B1, Highly Potent Antifungal Agents from the MyxobacteriumSorangium cellulosum

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