Photoinduced Redox Cascade Reaction of Isatins and Aliphatic Carboxylic Acids to Access 6‐Hydroxyindoloquinazolinones

Abstract

AbstractA visible‐light‐induced cascade reaction is described for the one‐pot synthesis of 6‐hydroxyindoloquinazolinones using isatins (or isatins and isatoic anhydrides) and aliphatic carboxylic acids. The method provides 36 desired products in 33–96 % yield, exhibiting broad substrate scope and good functional group tolerance. This approach utilizes inexpensive and commercially available starting materials, enabling the direct construction of high‐value complex structures under mild conditions without the need for photocatalyst, showcasing significant applicability and environmental friendliness.