Chiral inversion of the second generation IMiD? CC-4047 (ACTIMID?) in human plasma and phosphate-buffered saline

Author:

Teo Steve K.,Chen Yong,Muller George W.,Chen Roger S.,D. Thomas Steve,Stirling David I.,Chandula Reddy S.

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Pharmacology,Catalysis,Analytical Chemistry

Reference16 articles.

1. A Phase I study of an immunomodulatory thalidomide analogue (CC-4047) in relapse/refractory multiple myeloma. 31st Annual Meeting of the International Society for Experimental Hematology; 2002. Abstract 248.

2. Amino-substituted thalidomide analogs: Potent inhibitors of TNF-α production

3. Selection of Novel Analogs of Thalidomide with Enhanced Tumor Necrosis Factor α Inhibitory Activity

4. Therapeutic potential of TNF-α inhibitors old and new

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