Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions

Author:

Duarte João H.,Zelenay Santiago,Bergman Marie-Louise,Martins Ana C.,Demengeot Jocelyne

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference35 articles.

1. Foxp3+CD25+CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease;Sakaguchi;Immunol. Rev.,2006

2. Regulatory T cells in microbial infection;Demengeot;Springer Semin. Immunopathol.,2006

3. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases;Sakaguchi;J. Immunol.,1995

4. JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome;Chatila;J. Clin. Invest.,2000

5. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3;Bennett;Nat. Genet.,2001

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