Fully covered metallic stents for anastomotic biliary strictures after living donor liver transplantation

Author:

Komatsu Naohiro1ORCID,Ozawa Eisuke1,Fukushima Masanori1ORCID,Sawase Hironori1,Nagata Kazuyoshi1,Miuma Satoshi1,Miyaaki Hisamitsu1,Soyama Akihiko2,Hidaka Masaaki2,Eguchi Susumu2,Nakao Kazuhiko1

Affiliation:

1. Department of Gastroenterology and Hepatology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan

2. Department of Surgery Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan

Abstract

AbstractObjectivesAnastomotic biliary strictures (ABSs) are common complications following living donor liver transplantation (LDLT). We evaluated the feasibility of a novel removable, intraductal, fully covered, self‐expandable metallic stent (FCSEMS) for the treatment of ABSs following LDLT.MethodsNine patients with duct‐to‐duct ABSs that developed following LDLT were prospectively enrolled in this study. We placed a short FCSEMS with a long lasso and middle waist formation in each patient's ABS above the papilla and removed it 16 weeks later.ResultsThe FCSEMS placements were successful in all nine cases. Four patients experienced mild cholangitis, which was resolved with conservative treatment. Additionally, there was one case of distal migration. The FCSEMSs were successfully removed from all the patients, and the clinical success rate was 100%. Stricture recurrence occurred in one (11.1%) patient during the follow‐up period.LimitationsThe small number and lack of comparison with other types of FCSEMSs and plastic stents.ConclusionsIntraductal placement of FCSEMSs is useful for treating refractory ABSs after LDLT, although further studies are required with larger sample sizes.

Publisher

Wiley

Subject

Organic Chemistry,Biochemistry

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