Potency and Selectivity Optimization of Tryptophanol‐Derived Oxazoloisoindolinones: Novel p53 Activators in Human Colorectal Cancer-Reference-Cited by-同舟云学术

Potency and Selectivity Optimization of Tryptophanol‐Derived Oxazoloisoindolinones: Novel p53 Activators in Human Colorectal Cancer

Published:2020-09-02 Issue:1 Volume:16 Page:250-258
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Barcherini Valentina¹,Almeida Joana²,Lopes Elizabeth A.¹,Wang Mi³,Magalhães e Silva Diogo¹,Mori Mattia⁴,Wang Shaomeng⁵,Saraiva Lucília²,Santos Maria M. M.¹^ORCID

Affiliation:

1. Department of Therapeutic and Pharmaceutical Chemistry University of Lisbon Av. Prof. Gama Pinto 1649-003 Lisboa Portugal

2. Department of Biological Sciences University of Porto Rua de Jorge Viterbo Ferreira 228 4050-313 Porto Portugal

3. Rogel Cancer Center, Medical School University of Michigan Ann Arbor MI 48109 USA

4. Department of Biotechnology, Chemistry and Pharmacy University of Siena via Aldo Moro 2 53100 Siena Italy

5. Rogel Cancer Center, College of Pharmacy University of Michigan Ann Arbor MI 48109 USA

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202000522

Reference48 articles.

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2. Cancer statistics, 2019

3. Trends in Colorectal Cancer Incidence by Anatomic Site and Disease Stage in the United States From 1976 to 2005

4. Colorectal Cancer and Nutrition

5. Targeted cancer therapy

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