Drimane Derivatives as the First Examples of Covalent BH3 Mimetics that Target MCL‐1-Reference-Cited by-同舟云学术

Drimane Derivatives as the First Examples of Covalent BH3 Mimetics that Target MCL‐1

Published:2021-03-23 Issue:11 Volume:16 Page:1789-1798
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Daressy Florian¹²³,Malard Florian¹,Seguy Line⁴^ORCID,Guérineau Vincent¹^ORCID,Apel Cécile¹^ORCID,Dumontet Vincent¹,Robert Aude²⁵^ORCID,Groo Anne‐Claire⁴^ORCID,Litaudon Marc¹^ORCID,Bignon Jérôme¹,Desrat Sandy¹^ORCID,Malzert‐Fréon Aurélie⁴^ORCID,Wiels Joëlle²³,Lescop Ewen¹,Roussi Fanny¹^ORCID

Affiliation:

1. Institut de Chimie des Substances Naturelles CNRS UPR 2301 Université Paris-Saclay Avenue de la terrasse 91198 Gif-sur-Yvette Cedex France

2. Institut Gustave Roussy CNRS UMR8126 Université Paris-Saclay 114 rue Edouard-Vaillant 94805 Villejuif Cedex France

3. UMR9018 CNRS Institut Gustave Roussy Université Paris-Saclay 114 rue Edouard-Vaillant 94805 Villejuif France

4. Centre d'Etudes et de Recherche sur le Médicament de Normandie (CERMN) UNICAEN Normandie Université Boulevard Becquerel 14032 Caen Cedex France

5. Université Paris-Saclay Inserm Institut Gustave Roussy UMR1279 114 rue Edouard-Vaillant 94805 Villejuif France

Funder

Agence Nationale de la Recherche

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.202100011

Reference51 articles.

1. Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases

2. Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy

3. Life in the balance: how BH3-only proteins induce apoptosis

4. Overcoming Drug Resistance by Enhancing Apoptosis of Tumor Cells

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