Concise Synthesis of 1,4‐Benzoquinone‐Based Natural Products as Mitochondrial Complex I Substrates and Substrate‐Based Inhibitors

Author:

Han Zhenyu1,Angerer Heike23,Bischoff Iris4,Qin Yihan1,Stegmann Dennis5,Tuz Karina6,Fritz Günter5,Juarez Oscar6,Fürst Robert4,Lashley Dana1,Nasiri Hamid R.5ORCID

Affiliation:

1. Department of Chemistry William & Mary Williamsburg VA 23185 USA

2. Medical School, Institute of Biochemistry II Structural Bioenergetics Group Goethe University 60590 Frankfurt am Main Germany

3. Centre for Biomolecular Magnetic Resonance Institute for Biophysical Chemistry Goethe University 60438 Frankfurt am Main Germany

4. Institute of Pharmaceutical Biology Goethe University 60438 Frankfurt am Main Germany

5. Department of Cellular Microbiology University Hohenheim 70599 Stuttgart Germany

6. Department of Biological Sciences Illinois Institute of Technology Chicago IL 60616 USA

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

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