A synthetic anti-inflammatory sterol improves insulin sensitivity in insulin-resistant obese impaired glucose tolerance subjects

Author:

Reading Christopher L.1,Stickney Dwight R.1,Flores-Riveros Jaime1,Destiche Daniel A.1,Ahlem Clarence N.1,Cefalu William T.2,Frincke James M.1

Affiliation:

1. Harbor Therapeutics, Inc.; San Diego California USA

2. Pennington Biomedical Research Center; LSU System; Baton Rouge Louisiana California USA

Publisher

Wiley

Subject

Nutrition and Dietetics,Endocrinology,Endocrinology, Diabetes and Metabolism,Medicine (miscellaneous)

Reference34 articles.

1. HE3286: a novel synthetic steroid as an oral treatment for autoimmune disease;Ahlem;Ann N Y Acad Sci,2009

2. 7-Hydroxy androstene steroids and a novel synthetic analogue with reduced side effects as a potential agent to treat autoimmune diseases;Auci;Autoimmun Rev,2009

3. A synthetic androstene derivative and a natural androstene metabolite inhibit relapsing-remitting EAE;Offner;J Neuroimmunol,2002

4. A potential role for 5-androstene-3beta,7beta,17beta-triol in obesity and metabolic syndrome;Auci;Obesity (Silver Spring),2011

5. Studies of the pharmacology of 17alpha-ethynyl-androst-5-ene-3beta,7beta,17beta-triol, a synthetic anti-inflammatory androstene;Ahlem;Int J Clin Exp Med,2011

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