Advancing Prediction of Tissue Distribution and Volume of Distribution of Highly Lipophilic Compounds from a Simplified Tissue-Composition-Based Model as a Mechanistic Animal Alternative Method
Author:
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference46 articles.
1. Mechanistic animal-replacement approaches for predicting pharmacokinetics of organic chemicals;Poulin,1999
2. PhRMA CPCDC initiative on predictive models of human pharmacokinetics. 2. Comparative assessment of prediction methods of human volume of distribution;Jones;J Pharm Sci,2011
3. A unified algorithm for predicting partition coefficients for PBPK modeling of drugs and environmental chemicals;Peyret;Toxicol Appl Pharmacol,2010
4. Microsome composition-based model as a mechanistic tool to predict nonspecific binding of drugs in liver microsomes;Poulin;J Pharm Sci,2011
5. General approach for the calculation of tissue to plasma partition coefficients;Schmitt;Toxicol In Vitro,2008
Cited by 59 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Application of partition coefficient methods to predict tissue:plasma affinities in common farm animals: Influence of ionisation state;Toxicology Letters;2024-07
2. Relative Performance of Volume of Distribution Prediction Methods for Lipophilic Drugs with Uncertainty in LogP Value;Pharmaceutical Research;2024-05-08
3. A New Version of the Tissue Composition-Based Model for Improving the Mechanism-Based Prediction of Volume of Distribution at Steady-State for Neutral Drugs;Journal of Pharmaceutical Sciences;2024-01
4. The Application of a Physiologically Based Toxicokinetic Model in Health Risk Assessment;Toxics;2023-10-21
5. Development, testing, parameterisation, and calibration of a human PBK model for the plasticiser, di (2-ethylhexyl) adipate (DEHA) using in silico, in vitro and human biomonitoring data;Frontiers in Pharmacology;2023-03-23
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3